An unusual presentation of insulinoma and the serious consequences of delayed diagnosis

  • Z Dire University of the Witwatersrand
  • F J Raal University of the Witwatersrand
Keywords: HIV infection, hypoglycaemia, insulinoma, neuroglycopenia

Abstract

Insulinomas are rare functional neuroendocrine tumours. These tumours present with symptoms of hypoglycaemia, adrenergic and neuroglycopenic symptoms. Insulinomas are usually small in size, making them difficult to locate. Diagnosis is often delayed in these cases resulting in lasting neurological complications, often not reversible after surgical removal of the insulinoma. We report a case of a 33-year-old HIV-positive female with delayed presentation of an insulinoma. She presented with a long history of neurological symptoms with lasting neurological sequelae and poor functional status, during which time the diagnosis of insulinoma was repeatedly missed.

The full article is available at https://doi.org/10.1080/16089677.2020.1732690

Author Biographies

Z Dire, University of the Witwatersrand

Division of Endocrinology, Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

F J Raal, University of the Witwatersrand

Division of Endocrinology, Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

Published
2020-08-05
Section
Case Study