Leiomyoma: a rare cause of adrenal incidentaloma

  • Mohamed Alteer University of Stellenbosch
  • Brynn Ascott-Evans University of Stellenbosch
  • Magda Conradie University of Stellenbosch

Abstract

A 40-year-old, treatment-naïve, human immunodeficiency virus- (HIV) positive male was found to have a large right adrenal incidentaloma on ultrasound of the abdomen, which was confirmed on adrenal computed tomography imaging. The laboratory workup excluded functionality of the mass lesion. As the radiological examination of the mass raised the suspicion of a non-benign lesion, the patient underwent a right adrenalectomy. Histology, supported by a panel of immunohistochemical stains, confirmed the diagnosis of an adrenal leiomyoma. Most of the reported cases of adrenal leiomyomas in the literature are of patients with HIV and/or latent Epstein-Barr virus infections. This case illustrates that benign tumours, such as leiomyomas, can mimic the imaging phenotype of adrenal cortical carcinomas, and should be included in the differential diagnosis of adrenal incidentalomas, especially in the HIV-positive population.

Author Biographies

Mohamed Alteer, University of Stellenbosch
MBChB Registrar Department of Medicine Endocrine Division Tygerberg Academic Hospital
Brynn Ascott-Evans, University of Stellenbosch
MBChB, FCP(SA) Head Department of Medicine and Endocrine Division Tygerberg Academic Hospital University of Stellenbosch Cape Town
Magda Conradie, University of Stellenbosch
MBChB, PhD Consultant Department of Medicine and Endocrine Division Tygerberg Academic Hospital University of Stellenbosch Cape Town
Published
2013-01-24
Section
Case Study